Addax Biosciences is excited to share that our acid-free glyoxal formulation has been used in a recent study, demonstrating superior performance in preserving neuronal morphology and enhancing the detection of neurotransmitter receptor subunits during immunostaining.
Compared to traditional paraformaldehyde, the acid-free glyoxal (GAF) supplemented with sucrose provides researchers clearer insights into the intricate wiring of the brain, enabling a deeper understanding of neural connections and functionalities.
🔍 GAF maintains the delicate structure of neurons, crucial for accurate imaging and analysis.
🧠GAF facilitates robust detection of protein puncta, crucial for detailed molecular studies.
🔬 GAF ensures consistency and quality in your experimental outcomes, helping you push the boundaries of what’s possible in neuroscience.
To discover more about the research, we invite you to read the full article “Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome” published in Neuron, one of the most influential and relied upon journals in the field of neuroscience.
The study was conducted by esteemed researchers Piero Sanfilippo, Alexander J. Kim, Anuradha Bhukel, Juyoun Yoo, Pegah S. Mirshahidi, Vijaya Pandey, Harry Bevir, Ashley Yuen, Parmis S. Mirshahidi, Peiyi Guo, Hong-Sheng, James A. Wohlschlegel, Yoshinori Aso, Lawrence Zipursky.
Read the full study here: https://www.cell.com/neuron/fulltext/S0896-6273(23)00973-X