Formaldehyde (whose aqueous solution is called Formalin) is considered an irritant and toxic substance. Exposure to it may cause allergy, induce eczema and respiratory asthma. Furthermore, over the past decade, the scientific community has found out that inhalation of formaldehyde (which is highly volatile) may lead to cancer. In the European Union, Formaldehyde has been officially declared carcinogen. Its eradication from workplaces has been mandated by Regulation (EC) No 1907/2006 and Regulation (EC) No 1272/2008, starting from August 2017.
Formalin is widely used in plastic, wood, and paper production facilities. Additionally, it is employed as fixative solution for histology in hospitals and private laboratories where, only in Italy, about one million liters per year are consumed. In the healthcare system, thousands of workers (e.g. nurses, technicians, doctors, pathologists) are thus exposed to formaldehyde. Therefore, the balance between the diagnostic and scientific interest (i.e. patient’s health) and the protection of workers is set on a risks reduction basis defined as the “As Low As Reasonably Achievable (Risk)” Principle. In Italy, as in other countries of the European Union, this also results in strict obligations to protect the health of workers which may be in contact with the formaldehyde. Therefore, it is required to implement every possible technical, organizational and procedural initiative to minimize the risk to the worker’s health. Our project is aimed to fully resolve this social and scientific conundrum and offer a substitute to Formalin for tissue fixation.
Seal of Excellence UE – European Commission Horizon 2020
IPA4SME 2020 – Financial and expert support for intellectual property (IP) valorisation
Horizon 2020 – SME Instrument Project, Phase 1
Life science and social innovation awards, Start CUP
PwC Start UPS & Emerging Companies 2018
UniCredit start up award 2017
Finalist at the Italian Innovation Award
Collaboration with the A.O.U. Città della Salute e della Scienza in Turin, for the “Glyoxal in Endoscopy” project.
Collaboration with the Zooprophylactic Institute in Turin for GAF’s use in the veterinary sector, especially concerning neurological pathology.
Collaboration with the Polytechnic of Turin and the University of Turin for use of acid-free glyoxal as a fixative for valve and vascular prostheses.
Collaboration with the Italian Space Agency (ASI) for research and technological demonstrations on the International Space Station – VUS3: ISS4EXPLORATION.
Collaboration with the Dental School of University of Turin to develop innovative compounds capable to replace the use of Formaldehyde in Dentistry, particularly as disinfectant material during pulpotomy.
Collaboration with the University of Turin to improve research activity on the fixation of pathological tissues.
Collaboration with the University of Padova for GAF’s use as fixative in the veterinary sector.
Collaboration with the Montefiore Medical Center of New York, the University Hospital for Albert Einstein College of Medicine, for GAF’s use as fixative solution for kidney core biopsies.
Collaboration with the Candiolo Cancer Institute – IRCCS for the Immuno K-ELISA project and the study on the AD FORMALIN’s use.
Our company has received funding from the European Union’s Horizon 2020 Research and Innovation Programme under Grant Agreement No 8157692.
Our company has received funding from the Piedmont Region, in the context of regional operational program “Investimenti a favore della crescita e l’occupazione – FESR 2014/2020.